Table 3

NQO1 rs1800566 genotype and allelic variants in patients with multiple sclerosis (MS), and relation with the clinical evolutive type of MS
BOUT ONSET MS (RELAPSING REMITTING PLUS SECONDARY PROGRESSIVE MS) N Intergroup comparison values OR (95% CI), P PRIMARY PROGRESSIVE MS N (%, 95% C.I.) Intergroup comparison values OR (95% CI), P CONTROLS N (%, 95% C.I.)
rs1800566 GENOTYPE C/C 153 (61.9; 55.9-68.0) Reference 25 (58.1, 43.4-72.9) Reference 195 (62.9, 57.5-68.3)
C/T 85 (34.4; 28.5-40.3) 1.04 (0.72-1.51); 0.822 14 (32.6, 18.6-46.6) 1.05 (0.52-2.11), 0.891 104 (33.5, 28.3-38.8)
T/T 9 (3.6; 1.3-6.0) 1.04 (0.39-2.79); 0.928 4 (9.3, 0.6-18.0) 2.84 (0.84-9.59), 0.081 11 (3.5, 1.5-5.6)
Total 247 43 310
Allele C 391 (79.1; 75.6-82.7) Reference 64 (74.4, 65.2-83.6) Reference 494 (79.7, 76.5-82.8)
Allele T 103 (20.9; 17.3-24.4) 1.03 (0.76-1.40); 0.829 22 (25.6, 16.4-34.8) 1.35 (0.80-2.27), 0.262 126 (20.3, 17.2-23.5)
Total alleles 494 86 620

All subgroups were compared with control subjects. Major alleles and genotypes were assumed as reference values. P values correspond to logistic regression analyses.

AgĂșndez et al.

AgĂșndez et al. BMC Neurology 2014 14:87   doi:10.1186/1471-2377-14-87

Open Data