Table 2

Characteristics of patients with MS according to CCSVI status
Parameter Patients (n =67) Controls (n =21) p
CCSVI- CCSVI+ CCSVI- CCSVI+
n (%) 59 (88.1) 8 (11.9) 21(100) 0 (0) 0.1*
Female/male (%) 49.2/50.8 50.0/50.0 33.3/66.7 0/0 ns*
Age at onset (years ± SD) 27.5 ± 7.2 29.1 ± 9.7 - 0.6#
Disease duration (years ± SD) 8.4 ± 5.9 14.4 ± 6.5 - 0.01#
Disease course, n (%) - 0.12*
CIS 5 (8.5) 0
RR 38 (64.4) 3 (37.5)
CP 16 (27.1) 5 (62.5)
Total 59 (100) 8 (100)
MSSS (mean ± SD) 5.2 ± 2.2 7.4 ± 1.4 - 0.008#
EDSS (mean ± SD) 3.6 ± 2.0 5.85 ± 1.8 0.007#

CCSVI: chronic cerebrospinal venous insufficiency; CIS: clinically isolated syndrome; RR: relapsing-remitting; CP: chronic progressive (including secondary progressive and primary progressive); MSSS: Multiple Sclerosis Severity Score; EDSS: Expanded Disability Status Scale; * χ2; # ANOVA; values represent the means ± SD; ns: non-significant.

Krsmanović et al.

Krsmanović et al. BMC Neurology 2013 13:90   doi:10.1186/1471-2377-13-90

Open Data