Figure 1.

A-D: Skeletal muscle biopsy showing one ragged red fiber with histological methods (A-B: H&E, 10X ; B: GT, 40X). Histochemical reactions for COX (C, 10X) and COX-SDH (D, 10X) in cross serial sections show lack of COX activity in several skeletal muscle fibers (C), many of which also show increased SDH activity (D).E-H: Axial T2-weighted cerebral MRI sequences showing a cortico-subcortical fronto-parietal hyperintensity with restricted diffusion (not shown) consistent with acute ischaemic lesion and bilateral old ischaemic lesions in the right occipital and left temporal lobe.

Cheldi et al. BMC Neurology 2013 13:8   doi:10.1186/1471-2377-13-8
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