Figure 5.

Subtype analysis of GNE myopathy muscle fibres without structural abnormalities. A subtype analysis of the serial stainings from Figure 3 was performed in all GNE myopathy samples. A) A representative fibre appearing normal by H&E staining (black arrow, left micrograph) displays overexpresssion of αB-crystallin per immunohistochemical staining (white arrow, right micrograph). B) A representative fibre appearing normal by H&E staining (black arrow, left micrograph) displays overexpresssion of iNOS per immunohistochemical staining (white arrow, right micrograph). C) Quantitative analysis of serial stainings in all GNE myopathy subjects reveals that αB-crystallin and iNOS are the most prevalent markers in normal appearing muscle fibers (data presented as mean plus SEM).

Fischer et al. BMC Neurology 2013 13:24   doi:10.1186/1471-2377-13-24
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