Table 4

Relative risk of stroke and change in total cholesterol and triglyceride concentration between fibrates and placebo therapy
Source Triglyceride lowering Total cholesterol lowering Relative risk (RR) and 95% CI for stroke Relative risk (RR) and 95% CI for fatal stroke
BIP study [8] (2000) 11.0% 3.0% 0.93 (0.68, 1.27) -
VA-HIT study [10] (1999) 31.0% 4.0% 0.73 (0.53, 1.00) 0.33 (0.09, 1.23)
Acheson J [17] (1972) NR 6.4% 1.07 (0.70, 1.63) 0.41 (0.08, 2.00)
Veterans Administration Cooperative Study Group [18] (1973) 33.2% 3.7% 1.58 (0.97, 2.59) 0.70 (0.23, 2.19)
Coronary Drug Project Research Group [19] (1975) 22.3% 6.5% 1.11 (0.92, 1.34) -
WHO-COOP committee of principal Investigators [20] (1978) NR 9.0% 1.18 (0.71, 1.96) 0.99 (0.47, 2.08)
LEADER study [21,22] (2002) 23.4% 8.1% 1.23 (0.85, 1.77) 1.45 (0.62, 3.37)
E J Whitney [23] (2005) 21.5% 6.8% 0.90 (0.73, 1.12) -
FIELD study [24] (2005) 49.8% 19.6% 0.20 (0.01, 4.15) -
The ACCORD Study Group [25] (2010) 15.6% NR 1.06 (0.72, 1.56) 0.50 (0.15, 1.65)

Zhou et al.

Zhou et al. BMC Neurology 2013 13:1   doi:10.1186/1471-2377-13-1

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