Table 2

Design of trials included in the systematic review and meta-analysis
Source Blinding Intervention Control Follow-up (month) Lifestyle intervention Jadad score
BIP study [8] (2000) Double Bezafibrate 400 mg daily Placebo 74.4 Yes 4
VA-HIT study [10] (1999) Double Gemfibrozil 1200 mg daily Placebo 36–60 Yes 4
Acheson J [17] (1972) Open Clofibrate 1–2 g daily Corn oil then placebo 104 in treatment group 91 in placebo group NR 0
Veterans Administration Cooperative Study Group [18] (1973) Double Clofibrate 2 g daily Placebo 54 NR 1
Coronary Drug Project Research Group [19] (1975) Double Clofibrate 1.8 g daily Placebo 74.4 NR 4
WHO-COOP committee of principal Investigators [20] (1978) Double Clofibrate 1.6 g daily Olive oil Placebo 63.6 Yes 2
LEADER study [21,22] (2002) Double Bezafibrate 400 mg daily Placebo 55.2 NR 2
E J Whitney [23] (2005) Double Gemfibrozil 600 mg daily Placebo 30 Yes 3
FIELD study [24] (2005) Double Fenofibrate 200 mg daily Placebo 60 Yes 4
The ACCORD Study Group [25] (2010) Double Fenofibrate 160 mg daily Placebo 56.4 Yes 4

Zhou et al.

Zhou et al. BMC Neurology 2013 13:1   doi:10.1186/1471-2377-13-1

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