Table 4

Representativeness of the PSC vs non-PSC and the T25FW and non-T25FW cohorts
Characteristic PSC Non-PSC P-value T25FW Non-25FW P-value
Gender, % N = 2169 N = 1397 0.0384 N = 184 N = 3382 0.8527
Male 38 34 36 37
Female 62 66 64 63
Employment type, % N = 1048 N = 593 0.0004 N = 98 N = 1543 0.2362
Manual skilled 25 30 22 27
Manual unskilled 15 19 12 17
Non-Manual 60 51 66 56
Time since diagnosis,
N N = 1941 N = 1156 0.0330 N = 176 N = 2921 0.6199
Mean years 6.2 5.7 5.8 6.0
Mobility problems (PRF-reported), mean N = 2124 N = 1381 N = 181 N = 3324
Paraesis 0.90 0.86 0.2499 0.90 0.88 0.5122
Plegia 0.25 0.26 0.9536 0.25 0.25 0.9063
Spasticity 0.59 0.48 0.0001 0.61 0.54 0.1503
Muscle atrophy 0.15 0.09 0.0001 0.03 0.14 0.0085
Spasms/cramps 0.29 0.22 0.0001 0.30 0.26 0.2680
Footdrop 0.15 0.08 0.0001 0.13 0.12 0.4241
Ataxia 0.58 0.53 0.1016 0.54 0.56 0.9508
Dystonia 0.04 0.02 0.0091 0.04 0.03 0.4537
Fatigue 0.84 0.77 0.0219 0.85 0.81 0.3428
Most recent EDSS score
N N = 1845 N = 1211 0.5724 N = 151 N = 2905 0.4510
Mean 3.24 3.20 3.1 3.2

Pike et al.

Pike et al. BMC Neurology 2012 12:94   doi:10.1186/1471-2377-12-94

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