Table 4

Use of selected non-pain-related medications among study subjects*

Patients with painful neuropathies (N = 31,688)

Comparison group (N = 31,688)

P-Value


Number receiving


General anti-infectives systemic

14,451 (45.6)

10,953 (34.6)

<0.01


Cough and cold preparations

6,682 (21.1)

5,188 (16.4)

<0.01


Dermatologicals

7,464 (23.6)

5,415 (17.1)

<0.01


ACE inhibitors

8,421 (26.6)

5,327 (16.8)

<0.01


Antiulcerants

7,525 (23.7)

3,819 (12.1)

<0.01


Beta-blocking agents

6,148 (19.4)

4,446 (14.0)

<0.01


Anti-asthma and COPD products

5,534 (17.5)

3,450 (10.9)

<0.01


Drugs used in diabetes

4,553 (14.4)

3,996 (12.6)

<0.01


Diuretics

5,081 (16.0)

4,224 (13.3)

<0.01


Plain antispasmodics and anticholinergics

6,267 (19.8)

4,133 (13.0)

<0.01


Thyroid therapy

3,909 (12.3)

3,494 (11.0)

<0.01


Calcium antagonists

4,340 (13.7)

3,565 (11.3)

<0.01


Statins

4,377 (13.8)

1,900 (6.0)

<0.01


Antidiarrhoeals, oral electrolyte replacers and intestinal anti-inflammatories

3,336 (10.5)

2,116 (6.7)

<0.01


Non-narcotics and anti-pyretics

2,711 (8.6)

1,802 (5.7)

<0.01


Respiratory system and nasal preparations

2,558 (8.1)

1,722 (5.4)

<0.01


Angiotensin-II antagonists

2,532 (8.0)

1,764 (5.6)

<0.01


Heparins

2,412 (7.6)

1,573 (5.0)

<0.01


Ophthalmologicals

2,158 (6.8)

1,581 (5.0)

<0.01


Urologicals

2,614 (8.2)

1,406 (4.4)

<0.01


Systemic antihistamines

2,313 (7.3)

1,797 (5.7)

<0.01


Anti-gout preparations

2,305 (7.3)

1,531 (4.8)

<0.01


Nitrites and nitrates

2,016 (6.4)

991 (3.1)

<0.01


Mineral supplements

2,173 (6.9)

1,393 (4.4)

<0.01


Diagnostic agents

2,201 (6.9)

1,090 (3.4)

<0.01


Number receiving

<0.01


None of the above

5,114 (16.1)

8,329 (26.3)


1 of the above

5,020 (15.8)

6,513 (20.6)


2 of the above

4,329 (13.7)

4,460 (14.1)


3 of the above

3,612 (11.4)

3,415 (10.8)


≥ 4 of above

13,613 (43.0)

8,971 (28.3)


Any of above

26,574 (83.9)

23,359 (73.7)

<0.01


*Unless otherwise indicated, all values are number (%)

ACE: Angiotensin-converting enzyme; COPD: Chronic obstructive pulmonary disease

Berger et al. BMC Neurology 2012 12:8   doi:10.1186/1471-2377-12-8

Open Data