Table 2

Demographic and clinical characteristics of study subjects*

Patients with painful neuropathies (N = 31,688)

Comparison group (N = 31,688)

P-Value


Characteristic

---


Age group, years


18-44

8,621 (27.2)

8,621 (27.2)


45-54

6,056 (19.1)

6,056 (19.1)


55-64

6,577 (20.8)

6,577 (20.8)


≥ 65

10,434 (32.9)

10,434 (32.9)


Mean (SD)

56.1 (16.6)

56.1 (16.6)

---


Sex

---


Males

12,178 (38.4)

12,178 (38.4)


Females

19,510 (61.6)

19,510 (61.6)


Comorbidities


Infectious and parasitic diseases

5,822 (18.4)

3,308 (10.4)

<0.01


Neoplasms

1,787 (5.6)

1,281 (4.0)

<0.01


Any endocrine, nutritional and metabolic diseases, and immunity disorders

10,699 (33.8)

7,604 (24.0)

<0.01


Diseases of the blood and blood-forming organs

2,487 (7.8)

1,507 (4.8)

<0.01


Any anxiety

897 (2.8)

547 (1.7)

<0.01


Any depression

1,365 (4.3)

827 (2.6)

<0.01


Any disease of the nervous system and sense organs

14,691 (46.4)

5,854 (18.5)

<0.01


Any disease of the circulatory system

9,071 (28.6)

6,837 (21.6)

<0.01


Any disease of the respiratory system

10,485 (33.1)

7,786 (24.6)

<0.01


Any disease of the digestive system

9,970 (31.5)

5,488 (17.3)

<0.01


Any disease of the genitourinary system

5,019 (15.8)

3,497 (11.0)

<0.01


Complications of pregnancy, childbirth, and the puerperium

325 (1.0)

241 (0.8)

<0.01


Any disease of the skin and subcutaneous tissue

9,773 (30.8)

7,136 (22.5)

<0.01


Diseases of the musculoskeletal system and connective tissue


Back pain

15,444 (48.7)

693 (2.2)

<0.01


Cervical pain

2,011 (6.3)

615 (1.9)

<0.01


Arthritis

2,116 (6.7)

1,203 (3.8)

<0.01


Fibromyalgia

76 (0.2)

11 (0.0)

<0.01


Other body/joint pain

10,481 (33.1)

3,832 (12.1)

<0.01


Other

1,993 (6.3)

917 (2.9)

<0.01


Any disease of the musculoskeletal system and connective tissue

23,529 (74.3)

6,233 (19.7)

<0.01


Congenital anomalies

81 (0.3)

44 (0.1)

<0.01


Symptoms, signs, and ill- defined conditions


Fatigue

16 (0.1)

12 (0.0)

0.45


Headache

392 (1.2)

79 (0.2)

<0.01


Chest pain

387 (1.2)

216 (0.7)

<0.01


Abdominal pain

640 (2.0)

351 (1.1)

<0.01


Anxiety-related symptoms

0 (0.0)

0 (0.0)

---


Gastric-related symptoms

3 (0.0)

1 (0.0)

0.32


Other

6,420 (20.3)

2,989 (9.4)

<0.01


Any symptoms, signs, and ill-

7,320 (23.1)

3,507 (11.1)

<0.01


defined conditions


Any injury and poisoning

2,991 (9.4)

2,021 (6.4)

<0.01


Any sleep disorder

528 (1.7)

257 (0.8)

<0.01


Any of above**

31,447 (99.2)

24,768 (78.2)

<0.01


Number of comorbidities**

<0.01


0

241 (0.8)

6,920 (21.8)


1

3,632 (11.5)

6,757 (21.3)


2

4,617 (14.6)

5,648 (17.8)


3

4,883 (15.4)

4,222 (13.3)


≥ 4

18,315 (57.8)

8,141 (25.7)


*Unless otherwise indicated, all values are number (%).

**Excluding painful neuropathic disorders.

Berger et al. BMC Neurology 2012 12:8   doi:10.1186/1471-2377-12-8

Open Data