Table 1

Eligibility criteria for subject selection
Inclusion criteria
- All new consecutive patients of the participating memory clinics who are suspected of having a primary neurodegenerative disease
- Mini-Mental State Examination: ≥ 20
- Clinical Dementia Rating: 0 – 1
- Availability of a reliable informer or proxy (who visits or contacts the patient at least once a week)
Exclusion criteria
- Normal Pressure Hydrocephalus, Huntington’s disease
- Less than two years ago a transient ischaemic attack (TIA) or cerebral vascular accident (CVA) or TIA/CVA followed (within three months) by cognitive impairment
- Psychiatric history (schizophrenia, bipolar disorder or psychotic problems (not otherwise specified), less than 12 months ago)
- Major Depression according to the DSM-IV, less than 12 months ago
- Cognitive problems due to excessive alcohol use (based on clinical judgement)
- Brain tumour, epilepsy, encephalitis
- Probably not available for follow-up

Handels et al.

Handels et al. BMC Neurology 2012 12:72   doi:10.1186/1471-2377-12-72

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