Oculomotor performance as a function of age. Blue filled circles, control subjects (CTL); green diamonds, patients with only dopamine therapy (PD-DA) or with additional STN-DBS (PD-DBS-on, green diamonds framed by black squares); red triangles, DBS patients during stimulation off (PD-DBS-off). a, latency of reactive saccades; arrows link "on"- and "off"-data of those 4 Patients who exhibited latencies outside the CTL-range during "off" (range accidentally delimited by latency-on-age regression of PD-DA + DBS-on, green line); solid black arrows mark near significant changes (p < 0.059); dotted arrows, non-significant changes. b, c, gain of horizontal (b) and upward (c) smooth pursuit of a sinusoidally moving target (0.375 Hz, horizontal ± 20°, vertical ± 15°).
Pinkhardt et al. BMC Neurology 2012 12:5 doi:10.1186/1471-2377-12-5