Table 4

Independent predictors of 28-day mortality among 754 stroke patients
No imputation Trend test p-value Multiply imputed* Trend test p-value
RR** 95% CI RR** 95% CI
Male 1.59 (1.18, 2.14) 1.28 (1.07, 1.54)
Age 0.017 0.2
1st Quartile (31–53) 1.00 Reference 1.00 Reference
2nd Quartile (53–65) 0.92 (0.66, 1.28) 0.80 (0.66, 0.96)
3rd Quartile (66–76) 1.06 (0.73, 1.55) 0.97 (0.76, 1.24)
4th Quartile (77+) 1.60 (1.09, 2.37) 1.08 (0.85, 1.35)
Education 0.025 0.018
  <Primary school 1.00 Reference 1.00 Reference
  Completed secondary school 0.87 (0.64, 117) 1.01 (0.79, 1.28)
  ≥High school 0.57 (0.39, 0.85) 0.71 (0.57, 0.95)
Stroke subtype
Ischemic 1.00 Reference 1.00 Reference
Hemorrhagic 1.41 (1.03, 1.91) 1.49 (1.22, 1.82)
Prior Ranking score 0.18 <0.001
No disability 1.00 Reference 1.00 Reference
No significant disability 1.67 (1.28, 2.19) 1.86 (1.56, 2.21)
Slight disability 2.56 (1.48, 4.44) 2.40 (1.67, 3.45)
Moderate disability, able to walk 2.36 (0.99, 5.66) 2.35 (1.50, 3.68)
Moderate disability, unable to walk 1.74 (0.68, 4.48) 2.28 (1.42, 3.68)
Severe disability 0.60 (0.21, 1.75) 1.64 (1.23, 2.18)
Disturbed consciousness 4.65 (2.88, 7.50) 3.72 (2.62, 5.73)
Weakness 0.69 (0.53, 0.92) 0.66 (0.55, 0.78)
Speech disturbance 0.78 (0.47, 1.28) 1.54 (1.10, 2.16)
Diastolic blood pressure, per 10 mmHg 1.17 (1.09, 1.24) 1.05 (1.10, 2.16)
Glucose level, per 1 mmol/L 1.02 (1.01, 1.03) 1.02 (1.01, 1.03)
Hypercholesterolemia 1.42 (1.15, 1.77) 1.33 (1.12, 1.55)
Prior stroke 0.51 (0.27, 0.98) 0.62 (0.45, 0.84)

*multiple imputation resulted in 10 datasets that were combined to produce results.

**adjusted for all other variables.

Tirschwell et al.

Tirschwell et al. BMC Neurology 2012 12:150   doi:10.1186/1471-2377-12-150

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