Table 2

Retinal nerve fibre layer (RNFL) thickness in different sectors
Global (μm) Temporal (μm) Temporal superior (μm) Nasal superior (μm) Nasal (μm) Nasal inferior (μm) Temporal inferior (μm) Foveal (μm)
Controls (n=28) 99.82±7.41 76.50±9.18 136.86±12.32 103.36±18.89 75.18±12.21 109.50±19.86 145.39±11.82 230.21±13.64
HSP-a (n=28) 98.57±10.67 p=0.61 71.86±14.23 p=0.15 138.39±17.19 p=0.70 104.71±16.74 p=0.77 75±14.16 p=0.96 107.57±19.27 p=0.71 143.54±20.23 p=0.68 223.61±15.5 p=0.1
HSP-p (n=22) 100.82±9.76 p=0.88 76.09±10.48 p=0.69 139.59±17.31 p=0.88 104.82±16.43 p=0.91 76.18±14.91 p=0.92 110.45±19.47 p=1 146.36±20.27 p=0.91 221.23±15.28 p*<0.05
HSP-c (n=6) 90.33±10.58 p=0.06 56.33±16.24 p*<0.05 134±17.58 p=0.66 104.33±19.48 p=0.82 70.67±10.93 p=0.92 97±15.54 p=0.68 133.17±17.88 p*<0.05 232.33±14.15 p=0.08
SPG4 (n=13) 103.77±10.43 p=0.98 77.31±11.53 p=0.57 141.23±18.19 p=1 108.92±18.55 p=0.91 78.77±15.33 p=0.91 115.69±22.29 p=0.54 151.92±21.98 p=0.83 219.01±13.31 p*<0.05
SPG5 (n=1) 98 p=n.a. 81 p=n.a. 139 p=n.a. 86 p=n.a. 72 p=n.a. 107 p=n.a. 143 p=n.a. 209 p=n.a.
SPG7 (n=3) 88.67±18.45 p=0.48 51.33±27.43 p=0.13 141±23.9 p=0.69 92.33±19.86 p=0.81 77±17.45 p=0.26 92.67±7.09 p=0.78 124.33±21.22 p=0.10 222±12.77 p=0.14

Data shown in μm as mean ± SD. Statistic comparison of subgroups was performed to the corresponding number of healthy controls. P-value as revealed by ANOVA if applicable (with restrictions to SPG7-subgroup (n=3) and SPG5-subgroup (n=1), p* = p < 0.05 (p uncorrected)). For abbreviations, see Table  1.

Wiethoff et al.

Wiethoff et al. BMC Neurology 2012 12:143   doi:10.1186/1471-2377-12-143

Open Data