Table 2

Effect of patient, Parkinson's disease characteristics, and factors during hospitalization on deterioration of Parkinson's disease

Deterioration (N = 34)


Possible risk factors

N

P-value*

OR [95%-CI]

Gender

Male

25

0.39

Age

≥ 70 years

20

0.42

≥ 80 years

5

0.47

≥ 85 years

5

0.13

Disease duration

≥ 8 years

17

0.82

≥ 10 years

9

0.18

≥ 12 years

8

0.36

Hoehn&Yahr

stage ≥ II

27

0.50

stage ≥ III

27

0.07

On-off fluctuations

16

0.38

Cognitive problems

19

0.18

LED-value

> 500 mg/day

15

0.60

> 600 mg/day

15

0.07

> 700 mg/day

15

0.003

4.4 [1.7-11.5]

Complications ≥ 1

16

0.04

2.5 [1.1-5.6]

Confusion

10

0.23

Infections

7

0.00

6.7 [1.8-24.7]

wrong medication distribution

18

0.00

5.8 [2.5-13.7]

surgery

17

0.26

Non-neurologic ward

27

0.60

No involvement of paramedics

16

0.15

No-consultation of PD nurse specialist#

17

0.04

0.3 [0.1-0.7]


*P-value < 0.05 is considered significant

# Non-neurological ward

Abbreviations: N, number; OR, Odds-ratio; 95%-CI, 95%-confidence interval; LED, Levodopa equivalent dose; PD, Parkinson's Disease

Gerlach et al. BMC Neurology 2012 12:13   doi:10.1186/1471-2377-12-13

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