Table 1

Underlying diseases of patients positive and negative for JCV DNA on the basis of CSF specimens
Underlying disease No. (%) of JCV-positive patients No. (%) of JCV-negative patients
Category Subcategory
HIV infection / AIDS 16 (20.3) 63 (79.7)
Hematologic disorders 19 (23.5) 62 (76.5)
Acute myeloid leukemia 2 (16.7) 10 (83.3)
Acute lymphocytic leukemia 1 (14.3) 6 (85.7)
Chronic myeloid leukemia 0 (0) 2 (100)
Chronic lymphocytic leukemia 1 (50.0) 1 (50.0)
Adult T-cell leukemia 1 (50.0) 1 (50.0)
Hodgkin's lymphoma 1 (50.0) 1 (50.0)
Non-Hodgkin's lymphoma 6 (22.2) 21 (77.8)
Aplastic anemia 2 (50.0) 2 (50.0)
Primary immunodeficiency syndrome 2 (25.0) 6 (75.0)
Multiple myeloma 2 (66.7) 1 (33.3)
Primary macroglobulinemia 1 (100) 0 (0)
Myelodysplastic syndrome 0 (0) 6 (100)
Other 0 (0) 5 (100)
Autoimmune disorders 3 (6.0) 47 (94.0)
Multiple sclerosis 0 (0) 11 (100)
Rheumatoid arthritis 0 (0) 7 (100)
Systemic lupus erythematosus 3 (20.0) 12 (80.0)
Other 0 (0) 17 (100)
Other diseases 9 (10.0) 81 (90.0)
Cerebrovascular disorders 0 (0) 7 (100)
Solid-organ cancer 0 (0) 13 a (100)
Lung diseases 2 (66.7) 1 (33.3)
HCV-related liver disease 3 (37.5) 5 (62.5)
Renal diseases 0 (0) 11 b (100)
Sarcoidosis 3 (100) 0 (0)
Other 1 c (2.2) 44 d (97.8)
None/Unknown 1 (0.8) 118 (99.2)
Total 48 (11.5) 371 (88.5)

HCV, hepatitis C virus.

a Two patients underwent liver transplantation.

b Six patients underwent renal transplantation.

c The patient receiving the liver transplant had common variable immunodeficiency.

d One patient received heart and kidney transplants.

Nakamichi et al.

Nakamichi et al. BMC Neurology 2012 12:121   doi:10.1186/1471-2377-12-121

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