Table 1

Demographics and Standardized Neuropsychological Tests for the 4 Groups [ mean (standard deviation)]
Index NC (n=197) aMCI-sd (n=116) aMCI-md (n=195) AD (n=228) F(P)
Age 68.84 (7.70) 70.04 (9.13) 70.27 (8.75) 70.19 (9.17) 1.164 (0.323)
Education 9.42 (5.17) 9.66 (4.85) 9.14 (5.19) 9.21 (4.98) 0.313 (0.816)
Sex1 110:89 53:63 96:100 129:102 1.813 (0.143)
MMSE 27.05 (2.11) 25.59 (2.61) ** 25.17 (2.72) $$ 19.09 (2.58)## 414.451 (<0.001)
AVLT-delayed recall(M=12) 5.30 (2.01) 1.19 (1.31) ††** 1.01 (1.27) 0.27 (0.83)## 176.26 7(<0.001)
BNT(M=30) 23.56 (4.55) 23.56(4.75) †† 21.08 (3.51) $$ 18.01 (5.47)## 21.787 (<0.001)
SDMT 41.40 (11.98) 37.40 (10.57) †† 29.37 (13.48) $$ 20.16 (11.89)## 33.441 (<0.001)
CFT-Copy(M=36) 33.22 (3.42) 32.86 (3.13) † 29.73 (7.54) $ 24.74 (9.31)## 22.917(<0.001)
CFT-delayed recall(M=36) 15.47 (5.55) 11.69 (7.39) † 9.07 (5.58) $$ 4.15 (3.34) ## 38.909(<0.001)
CWT-CR(M=50) 45.73 (3.94) 42.96 (9.61) † 38.70 (10.43) $$ 29.50 (13.68)## 33.370(<0.001)
TMT-partA(s) 55.08 (20.78) 64.43 (25.25) †† 84.66 (36.57) $$ 118.30 (48.31) ## 36.214(<0.001)
TMT-part B(s) 155.89 (63.99) 172.08 (68.55)†† 250.37(107.90)$$ 331.28(131.65)## 32.921(<0.001)
CESD 11.43(2.24) 13.67(3.12) 10.30(2.79) 10.64(3.06) 1.329(0.266)

Comparison between NC group and aMCI-sd group is marked behind ‘aMCI-sd group’; ** P<0.01.

Comparison between aMCI-sd group and aMCI-md group is marked behind ‘aMCI-sd group’; † P<0.05; †† P<0.01.

Comparison between aMCI-md group and AD group is marked behind ‘aMCI-md group’; $ P<0.05; $$ P<0.01.

Comparison between NC group and AD group is marked behind ‘AD group’. # P<0.05; ## P<0.01.

AVLT: Auditory Verbal Learning Test; BNT: Boston Naming Test; SDMT: Symbol Digit Modalities Test; CFT: Rey-Osterrieth Complex Figure Test; CWT-CR: Card C right of Stroop Color-Word Test; TMT: Trail Making Test; CESD: Center for Epidemiologic Studies Depression.

1 chi-square test, M=maximum.

Guo et al.

Guo et al. BMC Neurology 2012 12:119   doi:10.1186/1471-2377-12-119

Open Data