Plasma 25(OH)D concentrations between RRMS patients and HC during summer and winter. Plasma 25(OH)D concentrations (mean + SD) were significantly lower (p = 0.0001) in RRMS patients (n = 40) compared to HC (n = 40) during the winter months. Differences in plasma 25(OH)D concentrations were not detected (p = 0.2) between patients and HC during the summer months. RRMS and HC had higher plasma 25(OH)D concentrations in summer months compared to winter months (p = 0.05 and p = 0.03, respectively). MS: Multiple sclerosis patients. HC: Healthy controls.
Grau-López et al. BMC Neurology 2012 12:103 doi:10.1186/1471-2377-12-103