Open Access Highly Accessed Research article

EEG spectral coherence data distinguish chronic fatigue syndrome patients from healthy controls and depressed patients-A case control study

Frank H Duffy*, Gloria B McAnulty, Michelle C McCreary, George J Cuchural and Anthony L Komaroff

BMC Neurology 2011, 11:82  doi:10.1186/1471-2377-11-82

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Including insomniac/sleep deprevation patients in future studies?

John Mitchell jr   (2011-07-08 17:23)  n/a email

One of the most distressing facets of CFS is the disrupted/interrupted sleep patterns experienced by many patients, which have a profound impact on quality of life. As a longtime CFS patient disrupted sleep was one of my first symptoms of illness, long before I became disabled due to cognitive dysfunction, weakness and post-exertional malaise, with the main problem being that I wake up from sleeping after a couple hours and then constantly awaken and try to go back to sleep for the rest of the night, every night. This has went on for the past decade, leaving me severely sleep deprived, and seems to fit with the reduced stage 4 sleep and alpha wave intrusion reported in several CFS sleep studies.

Although I am not educated on the techniques involved in this study, it would seem that variables such as insomnia and/or sleep deprivation would plausibly affect brain function in a manner distinct from depression and would possibly make for good comparison groups in future studies.

Thank you very much to the authors for your work on this disease.

Competing interests

CFS patient


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