Table 5

Meta-analysis summary odds ratios (95% CI) for the association of the T allele homozygosity with migraine

All migraine

MA only

MO only


(15 studies)

(15 studies)

(4 studies)


N = 4,365 cases

N = 3,862 cases

N = 503 cases

N = 30,110 controls

N = 30,110 controls

N = 674 controls


All studies

1.37 (1.07-1.76) "a"

1.42 (1.10-1.82) "a"

1.16 (0.36-3.76)


Excluding 1 study of women only "b"

1.46 (1.11-1.92) "a"

1.54 (1.17-2.02) "a"

1.16 (0.36-3.76)


Ethnic ancestry


European

1.20 (0.95-1.53)

1.28 (1.002-1.63) "a"

0.73 (0.24-2.24)


Non-European

3.46 (1.22-9.82) "a"

2.81 (0.84-9.44)

------- "c"


"a" Statistically significant.

"b" All studies included men and women except for Schurks et al 2008 which enrolled only women.

"c" No summary OR was computed, since there was only 1 study.

Samaan et al. BMC Neurology 2011 11:66   doi:10.1186/1471-2377-11-66

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