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Open Access Research article

Suprasellar cysts: clinical presentation, surgical indications, and optimal surgical treatment

Song-Bai Gui1, Xin-Sheng Wang1*, Xu-Yi Zong1, Ya-Zhuo Zhang12 and Chu-Zhong Li2

Author Affiliations

1 Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

2 Beijing Neurosurgical Institute, Beijing, China

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BMC Neurology 2011, 11:52  doi:10.1186/1471-2377-11-52

Published: 18 May 2011

Abstract

Background

To describe the clinical presentation of suprasellar cysts (SSCs) and surgical indications, and compare the treatment methods of endoscopic ventriculocystostomy (VC) and ventriculocystocisternotomy (VCC).

Methods

We retrospectively reviewed the records of 73 consecutive patients with SSC who were treated between June 2002 and September 2009. Twenty-two patients were treated with VC and 51 with VCC. Outcome was assessed by clinical examination and magnetic resonance imaging.

Results

The patients were divided into five groups based on age at presentation: age less than 1 year (n = 6), 1-5 years (n = 36), 6-10 years (n = 15), 11-20 years (n = 11), and 21-53 years (n = 5). The main clinical presentations were macrocrania (100%), motor deficits (50%), and gaze disturbance (33.3%) in the age less than 1 year group; macrocrania (75%), motor deficits (63.9%), and gaze disturbance (27.8%) in the 1-5 years group; macrocrania (46.7%), symptoms of raised intracranial pressure (ICP) (40.0%), endocrine dysfunction (40%), and seizures (33.3%) in the 6-10 years group; symptoms of raised ICP (54.5%), endocrine dysfunction (54.5%), and reduced visual field or acuity (36.4%) in the 11-20 years group; and symptoms of raised ICP (80.0%) and reduced visual field or acuity (40.0%) in the 21-53 years group. The overall success rate of endoscopic fenestration was 90.4%. A Kaplan-Meier curve for long-term efficacy of the two treatment modalities showed better results for VCC than for VC (p = 0.008).

Conclusions

Different age groups with SSCs have different main clinical presentations. VCC appears to be more efficacious than VC.

Keywords:
Suprasellar cyst; clinical presentation; endoscopic fenestration; outcome