Quantification of mtDNA. Quantification of mtDNA depletion in muscle, liver and fibroblasts of the patient. mtDNA content was measured by qPCR and normalised to a nuclear gene (B2M). Control mean and +/-1SD: fibroblast 832 +/-280; skeletal muscle 2878 +/-766 and liver 1515 +/-192.
Schaller et al. BMC Neurology 2011 11:4 doi:10.1186/1471-2377-11-4