Figure 3.

Subcortical GM damage in MS. Subcortical atrophy, measured using FIRST (part of FSL 4.1: http://www.fmrib.ox.ac.uk/fsl/ webcite). Above: Effect sizes of subcortical atrophy in a cohort of 120 early RRMS patients, six years post-diagnosis. Below: Two examples of segmented subcortical structures in a healthy control (HC, above) and an age-matched RRMS patient (MS, below).

Hulst and Geurts BMC Neurology 2011 11:153   doi:10.1186/1471-2377-11-153
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