Table 6

Relationship between the venous hemodynamic severity score (VHISS) and quantitative brain parenchyma venous vasculature in multiple sclerosis patients on pre-and post-contrast susceptibility-weighted images.

Pre-contrast

MS

(n = 59)

RR

(n = 41)

SP

(n = 18)

r

p

r

p

r

p


ATVV for all vein diameters (ml)

-0.54

< .0001

-0.7

< .0001

-0.17

.500


ATVV with diameter < 0.3 mm (ml)

-0.52

< .0001

-0.67

< .0001

-0.24

.340


Venous intracranial fraction

-0.54

< .0001

-0.67

< .0001

-0.12

.653


Average distance from vein (mm)

0.64

< .0001

0.73

< .0001

0.21

.413


Post-contrast

MS

(n = 48)

RR

(n = 36)

SP

(n = 12)

r

p

r

p

r

p


ATVV for all vein diameters (ml)

-0.46

< .0001

-0.47

< .0001

-0.23

.425


ATVV with diameter < 0.3 mm (ml)

-0.48

< .0001

-0.53

< .0001

-0.14

.722


Venous intracranial fraction

-0.57

< .0001

-0.6

< .0001

-0.28

.354


Average distance from vein (mm)

0.62

< .0001

0.72

< .0001

0.26

.324


MS - Multiple Sclerosis; RR - Relapsing-Remitting; SP - Secondary Progressive; ATVV - apparent total venous volume;

The relationship between VHISS and quantitative brain parenchyma venous was explored using the Spearman rank correlation coefficient.

Zivadinov et al. BMC Neurology 2011 11:128   doi:10.1186/1471-2377-11-128

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