Table 5

Quantitative brain parenchyma venous vascular assessment in multiple sclerosis patients and healthy controls, according to CCSVI status on pre-contrast susceptibility-weighted images.

Total CCSVI

(n = 53)

Mean (SD)

Total No CCSVI

(n = 39)

Mean (SD)

p-value


ATVV for all vein diameters (ml)

67.2 (17.8)

78.3 (16.6)

.003


ATVV with diameter < 0.3 mm (ml)

45.1 (11)

51 (9.4)

.003


Venous intracranial fraction

0.059 (0.02)

0.067 (0.01)

.044


Average distance from vein (mm)

1.25 (0.2)

1.1 (0.1)

< .0001


MS CCSVI

(n = 47)

MS No CCSVI (n = 12)


ATVV for all vein diameters (ml)

65.1 (17.1)

70 (8)

NS


ATVV with diameter < 0.3 mm (ml)

44 (10.8)

47 (4.5)

NS


Venous intracranial fraction

0.059 (0.02)

0.066 (0.01)

.084


Average distance from vein (mm)

1.29 (0.2)

1.08 (0.02)

.01


CCSVI - chronic cerebrospinal venous insufficiency; MS - Multiple Sclerosis; NS - non significant; ATVV - apparent total venous volume; ml - milliliters; mm - millimeters

The differences between the study groups were tested using the Mann-Whitney rank sum test.

Zivadinov et al. BMC Neurology 2011 11:128   doi:10.1186/1471-2377-11-128

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