The images display minimum projection (mIP) (horizontal upper row), apparent total venous volume (ATVV) (horizontal middle upper row), ATVV with a diameter < .3 mm (horizontal middle lower row) and average distance from voxel (DFV) map (horizontal lower row) for a healthy control (HC) (vertical left column), relapsing-remitting (RR) (vertical middle column) and secondary progressive (SP) (vertical right column) multiple sclerosis patients. The images of ATVV and ATVV with a diameter < .3 mm display the differences between HC, RR and SP MS patients [please note decreased ATVV (represented in light blue for ATVV and light green for ATVV with a diameter < .3 mm)] especially in the ventricular, periventricular white matter, deep gray matter and cortical structures between HC and MS patients, but no difference between RR and SP MS patients. The DFV maps show the differences between HC, RR and SP MS patients (please note that the green color represents distance closer to the veins, whereas the yellow and orange colors represent longer distance to the veins). RR and SP MS show more yellow and orange color compared to HC.
Zivadinov et al. BMC Neurology 2011 11:128 doi:10.1186/1471-2377-11-128