Table 3

Comparisons of treatment effects on disease recovery at 3 months between direct and network meta-analyses

Time at assessment

Intervention Group

Reference Group

Direct meta-analysis

Network meta-analysis

Discrepancy


n

OR

95% CI

SE

n

OR

95% CI

SE

Z

P value


3 month

Acy + Pred

Pred

409

1·39

0·52-3·75

0·32

773

1·24

0·79-1·94

0·28

0.27

0.788

Val + Pred

Pred

637

1·17

0·75-1·81

0·22

887

1·02

0·73-1·42

0·17

0·49

0·621

Acy

Pred

351

0·26

0·15-0·46

0·28

744

0·44

0·28-0·68

0·10

-1·77

0·077

Val

Pred

417

0·64

0·43-0·95

0·21

774

0·60

0·42-0·87

0·11

0·27

0·785

Plac

Pred

665

0·50

0·36-0·70

0·17

895

0·54

0·40-0·74

0·09

-0·40

0·689

Acy+Pred

Acy

247

2·45

1·33 - 4·53

0·29

383

2·84

1·68 - 4·78

0·75

0·83

0·20

Val+Pred

Acy

-

-

-

-

497

2·32

1·37 - 3·93

0·62

-

-

Val

Acy

-

-

-

-

384

1·37

0·79 - 2·37

0·38

-

-

Plac

Acy

245

1·14

0·65 - 1·98

0·27

505

1·25

0·78 - 1·98

0·29

-0·23

0·41

Acy+Pred

Val

-

-

-

-

413

2·06

1·20 - 3·56

0·57

Val+Pred

Val

413

1·55

1·02 - 2·35

0·20

527

1·69

1·16 - 2·48

0·33

-0·22

0·411

Plac

Val

413

0·97

0·65 - 1·45

0·20

535

0·91

0·63 - 1·31

0·17

0·24

0·404

Acy+Pred

Plac

246

2·16

1·17 - 4·00

0·29

534

2·27

1·31 - 2·66

0·55

-0·08

0·468

Val+Pred

Plac

412

1·59

1·05 - 2·42

0·20

648

1·87

1·31 - 2·66

0·34

-0·41

0·340

Acy+Pred

Val+Pred

-

-

-

-

526

1·22

0·72 - 2·06

0·32

-

-


6 month

Acy + Pred

Pred

441

1·63

0·47 - 5·75

0·83

758

1·74

0·93-3·24

0·56

-0·07

0·474

Val + Pred

Pred

637

1·58

0·55 - 4·48

0·40

857

1·15

0·78-1·69

0·23

0·67

0·246

Acy

Pred

250

0·15

0·04 - 0·41

0·25

660

0·33

0·18-0·61

0·10

-2·93

0·002

Val

Pred

417

0·55

0·36 - 0·85

0·21

744

0·55

0·37-0·81

0·11

0·00

0·500

Plac

Pred

665

0·44

0·17 - 1·14

0·34

865

0·62

0·43-0·88

0·11

-0·96

0·169

Acy+Pred

Acy

247

3·6

1·54 - 9·07

0·41

344

5·21

2·48 - 10·94

1·97

-0·18

0·427

Val+Pred

Acy

-

-

-

-

443

3·45

1·78 - 6·68

1·16

-

-

Val

Acy

-

-

-

-

330

1·64

0·85 - 3·18

0·55

-

-

Plac

Acy

245

1·63

0. 80 - 3·34

0·34

451

1·84

1·02 - 3·33

0·56

-0·18

0·427

Acy+Pred

Val

-

-

-

-

428

3·17

1·57 - 6·40

1·14

Val+Pred

Val

413

1·89

1·23 - 2·92

0·21

527

2·10

1·40 - 3·15

0·44

-0·22

0·414

Plac

Val

413

1·16

0·77 - 1·76

0·20

535

1·12

0·76 - 1·65

0·22

0·12

0·453

Acy+Pred

Plac

246

2·21

0·89 - 5·82

0·43

549

2·83

1·46 - 5·47

0·95

-0·24

0·406

Val+Pred

Plac

412

1·63

1·05 - 2·51

0·21

648

1·86

1·26 - 2·77

0·38

-0·30

0·381

Acy+Pred

Val+Pred

-

-

-

-

541

1·51

0·75 - 3·05

0·54

-

-


Numthavaj et al. BMC Neurology 2011 11:1   doi:10.1186/1471-2377-11-1

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