Upper image shows genes in linkage disequilibrium with the SNP rs1022442 and lower plot shows the distribution of SNP rs1022442 and nearby SNPs. In lower plot, the x-axis indicates loci on chromosome 21 and y-axis indicates p-values (-log10(observed GENO_2DF p-values)). Green arrow indicates rs1022442 (p = 2.75 × 10-7) on loci 21277717 and pink arrow indicates rs2826629 (p = 8.40 × 10-5) on loci 21265887.
Han et al. BMC Neurology 2010 10:90 doi:10.1186/1471-2377-10-90