Email updates

Keep up to date with the latest news and content from BMC Neurology and BioMed Central.

Open Access Case report

Recurrent myelitis after allogeneic stem cell transplantation. Report of two cases

Martin Voß and Felix Bischof*

Author Affiliations

Hertie Institute for Clinical Brain Research, Department of General Neurology, University of Tübingen, Hoppe-Seyler-Strasse 3, 72076 Tübingen, Germany

For all author emails, please log on.

BMC Neurology 2010, 10:76  doi:10.1186/1471-2377-10-76

Published: 1 September 2010

Abstract

Background

Allogeneic and autologous haematopoietic stem cell transplantation are established treatment options for haematological malignancies and may possibly be employed to treat a range of genetic and autoimmune diseases.

Case presentation

We report two patients who developed an acute myelitis within their thoracic spinal cord after allogeneic stem cell transplantation. Myelitis in these patients was not related to graft versus host disease or immune reconstitution and was responsive to intravenous methylprednisolone and cyclophosphamide.

Conclusions

Myelitis is a possibly disabling consequence of haematopoietic stem cell transplantation.