Table 2

ORs for Parkinson's disease in relation to alcohol drinking during "peak" period

Alcohol drinking during "peak" period a

n (%)

Crude OR

(95% CI)

Adjusted ORb

(95% CI)

Adjusted ORc

(95% CI)


Cases (N = 214)

Controls (N = 327)


Frequency

Non-drinker

115 (53.7)

181 (55.4)

1.00

1.00

1.00

< 6 days per week

63 (29.4)

77 (23.6)

1.29 (0.86-1.93)

1.46 (0.90-2.36)

1.29 (0.78-2.13)

≥ 6 days per week

36 (16.8)

69 (21.1)

0.82 (0.51-1.30)

1.13 (0.61-2.10)

0.96 (0.50-1.81)

P for trend

0.70

0.50

0.96

Amount per day (ethanol, g)

Non-drinker

115 (53.7)

181 (55.4)

1.00

1.00

1.00

0.1-65.9

46 (21.5)

73 (22.3)

0.99 (0.64-1.53)

1.20 (0.72-1.97)

1.07 (0.64-1.80)

≥ 66.0

53 (24.8)

73 (22.3)

1.14 (0.75-1.74)

1.75 (0.97-3.20)

1.46 (0.79-2.71)

P for trend

0.58

0.07

0.26

Amount per week (ethanol, g)

Non-drinker

115 (53.7)

181 (55.4)

1.00

1.00

1.00

0.1-219.3

41 (19.2)

73 (22.3)

0.88 (0.56-1.38)

1.11 (0.67-1.83)

0.98 (0.58-1.65)

≥ 219.4

58 (27.1)

73 (22.3)

1.25 (0.82-1.90)

2.09 (1.13-3.91)

1.79 (0.95-3.39)

P for trend

0.38

0.03

0.11


OR, odds ratio; CI, confidence interval.

a Defined as period during which the subject's alcohol consumption was the highest.

b Adjusted for sex, age, region of residence, pack-years of smoking, years of education, body mass index, alcohol flushing status, and presence of medication history for hypertension, hypercholesterolemia, and diabetes.

c Adjusted for sex, age, region of residence, pack-years of smoking, years of education, body mass index, alcohol flushing status, presence of medication history for hypertension, hypercholesterolemia, and diabetes, dietary intake of caffeine, cholesterol, vitamin E, vitamin B6, iron, and dietary glycemic index.

Fukushima et al. BMC Neurology 2010 10:111   doi:10.1186/1471-2377-10-111

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