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Associations of cystatin C and biomarker levels at the baseline visit of the MESA study using adjusted linear regression, stratified by race/ethnicity |
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| White β coefficient (95% CI) |
African-American β coefficient (95% CI) |
Chinese β coefficient (95% CI) |
Hispanic β coefficient (95% CI) |
p-value for interaction |
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| CRP (log mg/L) |
0.61 (0.37, 0.84) |
0.34 (0.14, 0.53) |
-0.12 (-0.52, 0.28) |
0.13 (-0.06, 0.31) |
<0.001 |
| IL-6 (log pg/mL) |
0.62 (0.49, 0.75) |
0.36 (0.25, 0.47) |
0.26 (0.01, 0.51) |
0.26 (0.15, 0.36) |
<0.001 |
| ICAM-1 (ng/mL) |
100.4 (78.8, 122.0) |
66.2 (18.7, 113.7) |
30.8 (-9.9, 71.6) |
48.6 (11.0, 86.3) |
0.015 |
| Factor VIII (%) |
52.0 (38.3, 65.9) |
46.8 (23.5, 70.0) |
22.4 (9.0, 35.8) |
32.5 (21.3, 43.8) |
0.003 |
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All biomarker models adjusted for age, gender, race/ethnicity, smoking status, BMI, diabetes, hypertension, LDL, HDL, and use of statins. Beta coefficients are given per standard deviation of cystatin C | |||||
Keller et al. BMC Nephrology 2008 9:9 doi:10.1186/1471-2369-9-9 |
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