Table 4

Associations of cystatin C and biomarker levels at the baseline visit of the MESA study using adjusted linear regression, stratified by race/ethnicity

White β coefficient

(95% CI)

African-American β coefficient

(95% CI)

Chinese β coefficient

(95% CI)

Hispanic β coefficient

(95% CI)

p-value for interaction


CRP (log mg/L)

0.61 (0.37, 0.84)

0.34 (0.14, 0.53)

-0.12 (-0.52, 0.28)

0.13 (-0.06, 0.31)

<0.001

IL-6 (log pg/mL)

0.62 (0.49, 0.75)

0.36 (0.25, 0.47)

0.26 (0.01, 0.51)

0.26 (0.15, 0.36)

<0.001

ICAM-1 (ng/mL)

100.4 (78.8, 122.0)

66.2 (18.7, 113.7)

30.8 (-9.9, 71.6)

48.6 (11.0, 86.3)

0.015

Factor VIII (%)

52.0 (38.3, 65.9)

46.8 (23.5, 70.0)

22.4 (9.0, 35.8)

32.5 (21.3, 43.8)

0.003


All biomarker models adjusted for age, gender, race/ethnicity, smoking status, BMI, diabetes, hypertension, LDL, HDL, and use of statins.

Beta coefficients are given per standard deviation of cystatin C

Keller et al. BMC Nephrology 2008 9:9   doi:10.1186/1471-2369-9-9

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