Table 5

Immunohistological findings at presentation

Responders N = 24

Non responders N = 10

p


I. Glomeruli


PCNA(+) cells

38 ± 16

31 ± 16

NS

α-SMA(+)cells

30 ± 16

38 ± 17

NS

Monocytes/macrophages

16 ± 11

15 ± 8

NS

LFA-1β(+)cells

14 ± 5

22 ± 8

NS

TGF-β1 expression

1.0 ± 0.63

2.2 ± 0.84

0.046

ICAM-1 expression

1.67 ± 0.78

1.71 ± 0.75

NS

C5b-9 expression

2.14 ± 0.95

2.6 ± 0.54

NS


II. Tubulointerstitium


HLA-DR(+) cells

986 ± 702

1484 ± 1022

NS

PCNA(+)cells

845 ± 145

686 ± 160

NS

α-SMA(+)cells

732 ± 275

497 ± 224

NS

Monocytes/macrophages

580 ± 222

473 ± 144

NS

LFA-1β(+)cells

512 ± 151

460 ± 132

NS

ICAM-1 in tubules

29.3 ± 9.5

48.8 ± 4.9

<0.0001

C5b-9 in tubules

29.6 ± 8.5

38.9 ± 9.1

0.05

TGF-β1 in interstitium

1.57 ± 0.94

2.4 ± 0.55

NS

TGF-β1 in tubules

1.78 ± 0.80

2.4 ± 0.89

NS

ICAM-1in vessels

1.27 ± 0.46

1.10 ± 0.01

NS

C5b-9 in vessels

1.06 ± 0.26

1.01 ± 0.09

NS


Alexopoulos et al. BMC Nephrology 2006 7:16   doi:10.1186/1471-2369-7-16

Open Data