Table 2 |
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|
Number of cases and controls needed to detect a 2-fold risk (alpha 5%, 1-beta = 80%). Comparison of heavy analgesic use (top tertile in grams) vs. non use in the respective categories of analgesics. Important: the subcategories are not mutually exclusive and cannot be added up to 100%. |
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|
Prevalence in controls (%) |
Nb of cases |
Nb of controls |
|
|
|
|||
|
All analgesics (phenacetin-free) |
22.8 |
104 |
416 |
|
Phenacetin-containing |
2.5 |
616 |
2464 |
|
MONOS |
|||
|
Paracetamol |
5.3 |
308 |
1232 |
|
ASA |
15.7 |
129 |
516 |
|
Ibuprofen |
2.1 |
728 |
2912 |
|
Other monos |
5.0 |
324 |
1296 |
|
COMBIS |
|||
|
Paracetamol+caffeine |
0.1 |
14 670 |
58 680 |
|
Paracetamol+ASA |
0.9 |
1657 |
6628 |
|
Paracet+ASA+caffeine |
4.1 |
388 |
1552 |
|
Others+caffeine |
0.6 |
2470 |
9880 |
|
Other combis without caffeine |
3.5 |
449 |
1800 |
|
Other combis+caffeine |
3.3 |
475 |
1900 |
|
Combis with codeine or barbiturates |
1.9 |
654 |
2616 |
|
|
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|
Heinemann et al. BMC Nephrology 2005 6:9 doi:10.1186/1471-2369-6-9 |
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