Table 2 |
||||
| Baseline serum bicarbonate level correlated with other factors | ||||
| Univariate linear regression analysis | Multiple linear regression analysis | |||
| Difference in serum bicarbonate level | p | Difference in serum bicarbonate level | p | |
| Age (years) | −0.02 | 0.64 | ||
| Female (%) | 1.16 | 0.06 | 0.80 | 0.13 |
| Diabetes mellitus (%) | 1.35 | 0.03 | 1.28 | 0.033 |
| Hypertension (%) | 1.67 | 0.006 | 0.63 | 0.27 |
| BMI (kg/m2) | −0.045 | 0.73 | ||
| eGFR | 0.13 | 0.0001 | 0.094 | 0.0001 |
| Albumin level (g/dl) | 0.44 | 0.61 | ||
| Sodium level (mEq/l) | 0.23 | 0.08 | 0.07 | 0.52 |
| Potassium level (mEq/l) | −1.66 | 0.0045 | 0.035 | 0.95 |
| 24-hour urine protein excretion level (g/day) | −0.58 | 0.049 | −0.22 | 0.40 |
| RAAS inhibitor (%) | 1.59 | 0.08 | ||
| Loop diuretic use (%) | −0.64 | 0.31 | ||
| Sodium bicarbonate use (%) | −2.70 | 0.0002 | −1.18 | 0.10 |
Values are expressed as differences in serum bicarbonate level (estimated parameter) and p values. Multiple linear regression analysis variables include gender, diabetes, hypertension, eGFR, sodium level, potassium level, 24-hour urine protein excretion level, and sodium bicarbonate use.
Abbreviations: BMI Body mass index, eGFR Estimated glomerular filtration rate, RAAS Renin angiotensin aldosterone system.
Kanda et al. BMC Nephrology 2013 14:4 doi:10.1186/1471-2369-14-4
