Table 3

Comparison of various parameters in albuminuria stages of chronic kidney disease in type 2 diabetes patients (n=182)
A1 A2 A3 Total Jonckheere-Terpstra
Number (male/female) 108 (46 / 62) 47 (17 / 30) 27 (8 / 19) 182 (71 / 111) 0.075
Age (years) 60.0±14.0 63.5±13.5 62.0±12.7 60.4±14.4 0.199
BMI (kg/m2) 25.3±1.5 26.2±6.2 27.3±5.1 25.6±5.1 0.227
SBP (mmHg) 128.8±13.3 132.7±19.7 137.0±20.0 129.5±15.9 0.071
DBP (mmHg) 75.1±9.9 72.7±13.1 78.3±16.6 74.7±11.4 0.982
PG (mmol/L) 8.5±3.0 9.6±3.9 9.1±2.7 8.9±3.3 0.170
HbA1c (%) 7.27±0.87 7.51±1.35 7.61±1.41 7.35±1.12 0.611
HbA1c (mmol/mol) 75.5±9.0 78.0±14.0 79.0±14.6 76.3±11.6 0.611
ACR (mg/gCr) 11.2±6.2 110.7±83.4 1474±1444 196.6±655.0 5.06×10-23**
Cr (μmol/L) 69.0±40.7 73.4±19.4 114.9±53.9 74.3±39.8 2.44×10-4**
UN (mmol/L) 5.8±2.1 6.5±1.9 9.1±4.1 6.1±2.5 2.04×10-4**
eGFR (mL/s) 1.29±0.34 1.17±0.30 0.86±0.37 1.24±0.37 2.55×10-4**
Osmotic pressure (mmol/kg) 301.0±4.0 300.9±4.7 306.7±4.8 301.6±4.8 0.013*
T-Cho (mmol/L) 4.85±0.92 5.00±1.17 4.98±0.94 4.87±0.97 0.688
TG (mmol/L) 1.44±0.71 1.75±0.82 1.72±0.84 1.56±0.81 0.051
HDL-C (mmol/L) 1.57±0.49 1.52±0.51 1.56±0.54 1.56±0.49 0.413
LDL-C (mmol/L) 2.77±0.62 2.90±0.85 2.78±0.77 2.75±0.72 0.890
Log10Gal-9 (pg/mL) 1.97±0.43 1.90±0.45 1.98±0.30 1.96±0.42 0.374

BMI, body mass index; SBP, Systolic Blood Pressure; DPB, Diastolic Blood Pressure; PG, Plasma glucose; ACR, albumin / creatinine ratio; Cr, serum creatinine; UN, serum urea nitrogen; eGFR, estimated glomerular filtration ratio; T-Cho, Total cholesterol; TG, Triglyceride; HDL-C, HDL cholesterol; LDL-C, LDL cholesterol; Log10Gal-9, Log10galectin-9 (pg/mL). *, p < 0.05; **, p < 0.01.

Kurose et al.

Kurose et al. BMC Nephrology 2013 14:23   doi:10.1186/1471-2369-14-23

Open Data