Single measurements of NAG/Cr could not predict renal function deterioration in 1 year. As a whole, the patients with a high baseline urinary NAG/Cr (≥ 4.95 IU/g) demonstrated lower estimated GFRs at baseline and at 12 months (54.8 ± 19.3 vs. 75.3 ± 18.7, P < 0.001). However, annual decline of estimated GFRs were not different between high and low NAG/Cr groups. Subgroup analyses in the patients with baseline estimated GFR ≥ 60 and < 60 mL/min/1.73 m2 showed the similar results. Baseline estimated GFR (A); estimated GFR at 12 months (B); annual change in GFR over 12 months (C); percentage decrement in 12 months (D).
Park et al. BMC Nephrology 2012 13:93 doi:10.1186/1471-2369-13-93