Table 3

Associations of 25(OH)D levels and severity of albuminuria and Impaired eGFR
25(OH)D < 50 nmol/L, OR (95% CI)
Model 1a p Model 2b p Model 3c p
No Albuminuria Ref Ref Ref
Micro-albuminuria 2.06 (1.51-2.82) <0.001 1.80 (1.35-2.41) <0.001 1.59 (1.15-2.21) 0.007
Macro-albuminuria 1.99 (0.95-4.17) 0.07 1.70 (0.92-3.13) 0.09 1.22 (0.76-1.98) 0.39
25(OH)D < 50 nmol/L, OR (95% CI)
Model 1a Model 2b Model 3d
eGFR ≥60 Ref Ref Ref
eGFR 30-59 1.25 (0.78-2.02) 0.34 0.79 (0.53-1.16) 0.22 0.84 (0.56-1.26) 0.39
eGFR <30 9.31 (2.11-41.1) 0.004 5.93 (1.20-29.2) 0.03 4.46 (0.88-22.7) 0.07

CI – confidence interval, OR – odds ratio.

a unadjusted.

b adjusted for age and gender.

c adjusted for age, gender, diabetes, body mass index, triglycerides, cardiovascular disease, smoking, season, glomerular filtration rate and systolic blood pressure.

d adjusted for age, gender, diabetes, cholesterol, triglycerides, body mass index, smoking, ethnicity, cardiovascular disease, albuminuria and systolic blood pressure.

Damasiewicz et al.

Damasiewicz et al. BMC Nephrology 2012 13:55   doi:10.1186/1471-2369-13-55

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