Table 1

Characteristics of the study population
   Characteristics Men Women p
(n = 1980) (n = 2048)
Age (years) 52 (37; 65) 49 (36; 62) <0.01
Waist circumference (cm) 95.2 (87.5; 103.0) 81.5 (72.8; 92.2) <0.01
Physical activity (%) 41.5 43.7 0.17
Current smoker (%) 33.2 27.2 <0.01
Type 2 diabetes mellitus (%) 8.7 7.4 0.12
Hypertension (%) 62.7 41.7 <0.01
Serum IGF-I (ng/mL) 131 (103; 168) 134 (101; 172) 0.36
Serum IGFBP-3 (ng/mL) 1795 (1473; 2110) 1971 (1666; 2279) <0.01
Serum creatinine (mg/dL) 1.02 (0.94; 1.12) 0.87 (0.80; 0.94) <0.01
eGFR (mL/min/1.73m2) 83.02 (73.54; 92.97) 74.84 (66.83; 84.51) <0.01
CKD (%) 6.6 11.1 <0.01

Continuous data are given as median (25th; 75th quartile); nominal data are given as percentages. χ2-test (nominal data) or Kruskal-Wallis test (interval data). IGF-I = insulin-like growth factor I; IGFBP-3 = insulin-like growth factor-binding protein 3; eGFR = estimated glomerular filtration rate; CKD = chronic kidney disease defined as eGFR < 60 ml/min/1.73 m2.

Dittmann et al.

Dittmann et al. BMC Nephrology 2012 13:169   doi:10.1186/1471-2369-13-169

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