Table 3

Characteristics of all patients with ESKD secondary to HUS or other causes in Australia and New Zealand who underwent renal transplantation during the period 1963–2010, before and after matching for age, gender and transplant era
Before matching After matching
Characteristic HUS ESKD (n = 130) Other ESKD (n = 19549) P value Other ESKD Control (n = 130) P value
Age 25.2 ± 17.1 41.9 ± 14.8 <0.001 25.2 ± 17.0 0.98
Male gender 52 (40%) 11704 (60%) 0.001 52 (40%) 1.00
Racial origin 0.1 0.01
  European 118 (91%) 16738 (86%) 104 (80%)
  ATSI 1 (1%) 489 (3%) 3 (2%)
  MPI 4 (3%) 812 (4%) 11 (9%)
  Asian 1 (1%) 925 (5%) 9 (7%)
  Other 6 (5%) 585 (3%) 3 (2%)
Transplant era 0.01 1.00
  1963–1975 4(3%) 1939 (10%) 4 (3%)
  1976–1985 23 (18%) 3448 (18%) 22 (17%)
  1986–1995 22 (17%) 4595 (24%) 22 (17%)
  1996–2000 26 (20%) 2667 (14%) 27 (21%)
  2001–2005 24 (19%) 3150 (16%) 24 (19%)
  2006-2009 31 (24%) 3750 (19%) 31 (24%)
Ever smoked <0.001 0.37
  Current 10 (8%) 1560 (8%) 4 (3%)
  Former 14 (11%) 3668 (19%) 15 (12%)
  Never 82 (63%) 7788 (40%) 90 (69%)
  Missing 24 (19%) 6533 (33%) 21 (16%)
Hypertension 0.009 0.35
  Yes 54 (42%) 8562 (44%) 43 (33%)
  No 23 (18%) 1898 (10%) 24 (19%)
  Missing 53 (41%) 9089 (47%) 63 (49%)
Diabetes mellitus <0.001 0.007
  Yes 1 (1%) 2098 (11%) 11 (9%)
  No 113 (87%) 13435 (69%) 109 (84%)
  Missing 16 (12%) 4016 (21%) 10 (8%)
Chronic lung disease 0.007 0.28
  Yes 1 (1%) 581 (3%) 1 (1%)
  No 111 (85%) 14333 (73%) 119 (92%)
  Missing 18 (14%) 4637 (24%) 10 (8%)
Coronary artery disease 0.002 0.25
  Yes 4 (3%) 1201 (6%) 3 (2%)
  No 108 (83%) 13484(69%) 117 (90%)
  Missing 18 (14%) 4864 (25%) 10 (8%)
Peripheral vascular disease 0.003 0.28
  Yes 1 (1%) 703 (4%) 1 (1%)
  No 111 (85%) 14137 (72%) 119 (92%)
Missing 18 (14%) 4709 (24%) 10 (8%)
Cerebrovascular disease 0.025 0.03
  Yes 4 (3%) 391 (2%) 0 (0%)
  No 108 (83%) 14525(74%) 120 (92%)
  Missing 18 (14%) 4633 (24%) 10 (8%)
BMI (kg/m2) <0.001 0.86
Late referral 22.0 ± 5.9 24.7 ± 5.1 <0.001 21.8 ± 5.9 0.001
  Yes 35 (27%) 1742 (9%) 15 (12%)
  No 56 (43%) 10294 (53%) 84 (65%)
  Missing 39 (30%) 7513 (38%) 31 (24%)
Donor type <0.001 1.00
  Deceased 72 (55%) 14540 (74%) 72 (55%)
  Living 58 (45%) 5009 (26%) 58 (45%)
Subsequent grafts 0.06 0.44
  2 32 (19%) 2718 (12%) 22 (14%)
  3 3 (2%) 440 (2%) 4 (3%)
  4 1 (0%) 61 (0%) 0 (0%)
  5 0 (0%) 5 (0%) 0 (0%)

Abbreviations: ATSI Aboriginal and Torres Strait Islander, BMI Body mass index, MPI Maori and Pacific Islander, RRT Renal replacement therapy.

Tang et al.

Tang et al. BMC Nephrology 2012 13:164   doi:10.1186/1471-2369-13-164

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