Figure 7.

Simulated ENCX, [Na+]iand [Ca2+]i, assuming [Na+]o= 140 mM and [Ca2+]o= 1 mM. Abbreviations; ENCX: equilibrium potential of NCX1, [Na+]i : intracellular Na+ concentration, [Ca2+]i: intracellular Ca2+ concentration, [Na+]o: extracellular (basolateral) Na+ concentration and [Ca2+]o: extracellular (basolateral) Ca2+ concentration. Dotted circle indicates the simulated physiological [Ca2+]i, with [Na+]i at 17.5 mM and ENCX at −70 mV. Solid circle indicates the simulated [Ca2+]i with salt loading, with [Na+]i assumed at 22 mM and ENCX at −70 mV.

Yatabe et al. BMC Nephrology 2012 13:160   doi:10.1186/1471-2369-13-160
Download authors' original image