Table 4

Cox model measured hazardratios and 95% confidenceintervals of dementia associatedwith CKD and covariates
Crude Adjusted
Variable HR (95%CI) HR (95%CI)
Sex
Women 1.00 1.00
Men 0.94 (0.89-1.00) 0.97 (0.92-1.03)
Age, years
20–39 1.00 1.00
40–64 19.7 (10.2-38.0) 16.1 (8.35-31.2)
≥65 216 (112.-414) 133 (68.9-256)
CKD
No 1.00 1.00
Yes 1.68 (1.58-1.78) 1.41 (1.32-1.50)
Hypertension
No 1.00 1.00
Yes 4.10 (3.85-4.37) 1.17 (1.09-1.26)
Diabetes mellitus
No 1.00 1.00
Yes 2.14 (2.00-2.28) 1.25 (1.17-1.34)
Ischemic heart disease
No 1.00 1.00
Yes 3.11 (2.94-3.30) 1.00 (0.93-1.06)
Hyperlipidemia
No 1.00 1.00
Yes 1.35 (1.25-1.45) 0.89 (0.83-0.97)
Tobacco use disorder
No 1.00 1.00
Yes 1.00 (0.48-2.09) --
Alcoholism
No 1.00 1.00
Yes 1.78 (1.27-2.49) 3.05 (2.17-4.28)
Obesity
No 1.00 1.00
Yes 0.64 (0.41-1.00) 0.93 (0.59-1.46)
Atrial fibrillation
No 1.00 1.00
Yes 3.77 (3.19-4.45) 1.17 (0.99-1.39)
Parkinson's disease
No 1.00 1.00
Yes 6.92 (6.13-7.82) 1.80 (1.59-2.04)
Cerebrovascular disease
No 1.00 1.00
Yes 4.85 (4.57-5.14) 1.72 (1.61-1.84)
Major depressive disorder
No 1.00 1.00
Yes 2.68 (2.26-3.17) 1.95 (1.64-2.31)
Use of benzodiazepine
No 1.00 1.00
Yes 2.54 (2.37-2.71) 1.23 (1.14-1.32)
Use of aspirin
No 1.00 1.00
Yes 1.85 (1.71-2.00) 1.02 (0.95-1.11)
Use of other NSAIDs
No 1.00 1.00
Yes 1.54 (1.39-1.70) 1.01 (0.91-1.12)
Use of COX2
No 1.00 1.00
Yes 2.45 (2.31-2.60) 1.09 (1.02-1.16)

Adjusted for sex, age, CKD, hypertension, diabetes mellitus, ischemic heart disease, hyperlipidemia, alcoholism, obesity, atrial fibrillation, Parkinson's disease, cerebrovascular disease, major depressive disorder, use of benzodiazepine, aspirin, other NSAIDs and COX2.

Cheng et al.

Cheng et al. BMC Nephrology 2012 13:129   doi:10.1186/1471-2369-13-129

Open Data