Table 1

Clinical and biological data at admission in the intensive care unit
Characteristics   SIRS Sepsis
 n = 20 Total n = 40 Survivors n = 20 Non-survivors n = 20
Age (years) 55.4 ± 21.4 56.2 ± 19.8 52.7 ± 21.5 59.8 ± 17.8
Gender (n, %)
Male 7 (35) 28 (70) 16 (80) 8 (40)
Female 13 (65) 12 (30)* 4 (20) 12 (60)
temperature (°C) 37.31 ± 0.6 37.70 ± 1.1 37.97 ± 0.9 37.43 ± 1.1
WBC counts (×10∧9/L) 11.7 (9.3-13.0) 10.5 (7.7-17.0) 10.1 (7.7-12.6) 12.6 (7.4-21.9)
serum CRP (mg/dl) 3.4 (1.7-6.0) 11.6 (4.3-17.1)* 8.4 (3.1-15.5) 13.1 (6.1-18.2)
serum PCT (ng/ml) 0.3 (0.2-1.4) 1.9 (0.4-7.4) 1.9 (0.2-7.9) 2.0 (0.6-7.9)
serum sCD163 (ng/ml) 0.3 (0.2-0.4) 2.9 (1.6-11.3)* 1.7 (1.1-4.5) 10.2 (2.7-18.2)#
Renal characteristics
Urinary output (ml/Kg/hr) - 1.5 (1.1-1.9) 1.5 (1.0-1.9) 1.5 (1.1-2.1)
CCr(ml/min) - 90.1 (38.5-120.3) 94.3 (65.7-141.5) 53.1 (31.2-107.0)
SCr(μmmol/L) - 68.0 (55.8-130.7) 63.1 (53.6-96.6) 79.5 (62.1-110.1)
BUN(mmol/L) - 9.2 (6.5-15.6) 7.7 (5.9-10.3) 11.5 (8.9-29.9)#
APACHEII score 11.8 ± 6.7 16.6 ± 7.3* 12.3 ± 6.4 20.9 ± 5.5#
SOFA score - 7.9 ± 4.0 6.1 ± 2.9 9.6 ± 4.2#
MV (n, %) 13 (65) 31 (77.5) 14 (70) 17 (85)
CRRT (n, %) 1 (5) 12 (30)* 4 (20) 8 (40)
Etiological factors (n, %)
Pulmonary infection - 35 (87.5) 18 (90) 17 (85)
Abdominal infection - 9 (22.5) 6 (30) 3 (15)
Urinary tract infection - 11 (27.5) 8 (40) 3 (15)
Trauma/postoperative infection - 16 (40) 10 (50) 6 (30)
Bacteremia - 13 (32.5) 8 (40) 5 (25)
Catheter-related infections - 8 (20) 5 (25) 3 (15)
Others - 1 (2.5) 1 (5) 0 (0)
Pathogens (n, %)
Gram-positive bacteria - 11 (55) 8 (40)
Gram-negative bacteria - 18 (90) 15 (75)
Fungi - 11 (55) 11 (55)
underlying diseases (n, %)
Hypertension 6 (30) 12 (30) 6 (30) 6 (30)
Diabetes 2 (10) 7 (17.5) 3 (15) 4 (20)
COPD 0 (0) 3 (7.5) 3 (15) 0 (0)
Coronary heart disease 3 (15) 4 (10) 2 (10) 2 (10)
Immunosuppressed 0 (0) 7 17.5) 2 (10) 5 (25)
Nervous system disease 0 (0) 3 (7.5) 2 (10) 1 (5)
CKD 1 (5) 7 (17.5) 3 (15) 2 (10)

Quantitative data of normal distribution are presented as mean ± SD. Quantitative data of non-normal distribution are presented as median (25th and 75th percentiles). Qualitative data are presented as n (%).

APACHE score, Acute Physiologic Assessment and Chronic Health Evaluation II scores; SOFA score, Sequential Organ Failure Assessment scores; MV, mechanical ventilation; CRRT, continuous renal replacement therapy; COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease.

Su et al.

Su et al. BMC Nephrology 2012 13:123   doi:10.1186/1471-2369-13-123

Open Data