Table 4

Adherence to allopurinol dosing guidelines

Hande et al. Creatinine Clearance

Hande et al. Criteria Maintenance Dose of Allopurinol

Study Sample eGFR

Study Sample Initial Daily Dose of Allopurinol

mg


0

100 mg every 3 days

0-9

n

22

mean

240.91

dose ≤ Hande maintenance dose (%)

0


10

100 mg every 2 days

10-19

n

60

mean

233.14

dose ≤ Hande maintenance dose (%)

1.67


20

100 mg daily

20-39

n

114

mean

208.95

dose ≤ Hande maintenance dose (%)

34.21


40

150 mg daily

40-59

n

245

mean

236.35

dose ≤ Hande maintenance dose (%)

29.8


60

200 mg daily

60-79

n

471

mean

244.46

dose ≤ Hande maintenance dose (%)

35.46


80

250 mg daily

80-99

n

892

mean

249.58

dose ≤ Hande maintenance dose (%)

32.96


100

300 mg daily

100-119

n

909

mean

247.34

dose ≤ Hande maintenance dose (%)

95.93


120

350 mg daily

120-139

n

389

mean

253.09

dose ≤ Hande maintenance dose (%)

94.86


140

400 mg daily

140+

n

20

mean

250

dose ≤ Hande maintenance dose (%)

95


Fuldeore et al. BMC Nephrology 2011 12:36   doi:10.1186/1471-2369-12-36

Open Data