Table 4

Assessment of GFR changes with time using the original Cockcroft and Gault formula (CG), the BSA-modified-Cockcroft and Gault formula (BSA-CG) and the Abbreviated MDRD equation (A-MDRD), and the Mayo Clinic Quadratic equation.

Original Cockcroft and Gault formula (CG)

BSA-modified-Cockcroft and Gault formula (BSA-CG)

Abbreviated MDRD equation (A-MDRD)

Mayo Clinic Quadratic equation (MCQ)

Subgroup of patients with deteriorating renal function

(n = 65)

Spearman Correlation coefficient (95% confidence interval) with inulin clearance

r = 0.64 (0.43 – 0.78)

r = 0.67 (0.46 – 0.80)

r = 0.63 (0.41 – 0.78)

r = 0.49 (0.23 – 0.69)

Patients correctly classified as having deteriorating renal function

74%

77%

75%

74%

Bias (SD of bias) versus inulin clearance

0.98 (6.08)

1.37 (6.88)

1.30 (5.95)

1.32 (13.61)

Subgroup of patients with improving renal function

(n = 61)

Spearman Correlation coefficient (95% confidence interval) inulin clearance

0.75 (0.58 – 0.86)

r = 0.75 (0.58 – 0.86)

r = 0.72 (0.54 – 0.84)

r = 0.46 (0.19 – 0.67)

Patients correctly classified as having improving renal function

74%

74%

66%

68%

Bias (SD of bias) versus inulin clearance

3.08 (7.98)

2.98 (7.63)

1.27 (8.87)

3.02 (15.46)

Rostoker et al. BMC Nephrology 2009 10:16   doi:10.1186/1471-2369-10-16