Table 2

Polymorphisms used in genotyping assay.

Block and SNP (symbol)

Location

Gene name (OMIM #)*

Missing rate (%)


1:

C677T (V1)

1p36.3

MTHFR (MIM 607093)

0.32

Met235Thr (V2)

1q42

AGT (MIM 106150)

0.32

G664A (V3)

1p36.2

NPPA (MIM 108780)

0.32

T2238C (V4)

1p36.2

NPPA

0.32

Arg506Gln (V5)

1q23

F5 (MIM 227400)

0

Ser128Arg (V6)

1q23

SELE (MIM 131210)

0.32

Leu554Phe (V7)

1q23

SELE

0.32

2:

Thr71Ile (V8)

2p24

APOB (MIM 107730)

0.32

Arg3500Gln (V9)

2p24

APOB

0.32

3:

Pro12Ala (V10)

3p25

PPARG (MIM 601487)

0

A1166C (V11)

3q21-25

AGTR1 (MIM 106165)

0.32

4:

Gly460Trp (V12)

4p16.3

ADD1 (MIM 102680)

0.32

G-455A (V13)

4q28

FGB (MIM 124830)

0.32

5:

Arg16Gly (V14)

5q32-34

ADRB2 (MIM 109690)

0.32

Gln27Glu (V15)

5q32-34

ADRB2

0.32

G873A (V16)

5q23-31

ITGA2 (MIM 192974)

0.32

6:

C93T (V17)

6q27

LPA (MIM 152200)

1.94

G121A (V18)

6q27

LPA

1.29

Thr26Asn (V19)

6p21.3

LTA (MIM 153440)

0

Thr26Asn (V24)

6p21.3

TNFb

0

G-376A (V20)

6p21.3

TNF (MIM 191160)

0.32

G-308A (V21)

6p21.3

TNF

1.62

G-244A (V22)

6p21.3

TNF

1.62

G-238A (V23)

6p21.3

TNF

0

7:

Met55Leu (V25)

7q21.3

PON1 (MIM 168820)

0

Gln192Arg (V26)

7q21.3

PON1

0

Ser311Cys (V27)

7q21.3

PON2 (MIM 602447)

0.32

A-922G (V28)

7q36

NOS3 (MIM 163729)

0.32

C-690T (V29)

7q36

NOS3

0.32

Glu298Asp (V30)

7q36

NOS3

0.32

5G-6754G (V31)

7q21.3-22

PAI1 (MIM 173360)

0.32

G11053T (V32)

7q21.3-22

PAI1

0

8:

Trp64Arg (V33)

8p12-11.2

ADRB3 (MIM 109691)

1.62

T-93G (V34)

8p22

LPL (MIM 238600)

2.59

Asp9Asn (V35)

8p22

LPL

0

Asn291Ser (V36)

8p22

LPL

0.32

Ser447Ter (V37)

8p22

LPL

0

9:

Thr347Ser (V38)

11q23

APOA4 (MIM 107690)

0.65

Gln360His (V39)

11q23

APOA4

2.91

C-641A (V40)

11q23

APOC3 (MIM 107720)

9.06

C-482T (V41)

11q23

APOC3

0.65

T-455C (V42)

11q23

APOC3

0.32

C1100T (V43)

11q23

APOC3

1.29

C3175G (V44)

11q23

APOC3

0.32

T3206G (V45)

11q23

APOC3

0.32

5A(-1171)6A (V46)

11q23

MMP3 (MIM 185250)

0.32

G20210A (V47)

11p11-q12

F2 (MIM 176930)

0

10:

Trp493Arg (V48)

12p13

SCNN1A (MIM 600228)

0.32

Ala663Thr (V49)

12p13

SCNN1A

0.65

C825T (V50)

12p13

GNB3 (MIM 139130)

0.32

11:

-323 10-bp Del/Ins (V51)

13q34

F7 (MIM 227500)

0.32

Arg353Gln (V52)

13q34

F7

0.32

12:

C-480T (V53)

15q21-23

LIPC (MIM 151670)

0

13:

C-631A (V54)

16q21

CETP (MIM 118470)

0.32

C-629A (V55)

16q21

CETP

0.32

Ile405Val (V56)

16q21

CETP

0.32

Asp442Gly (V57)

16q21

CETP

0.32

Interon 14 G+1A (V58)

16q21

CETP

0

Intron 14(+3)Tins (V59)

16q21

CETP

0

Intron 1 TaqIB +/- (V60)

16q21

CETP

0

14:

Intron 16 Ins/Del (V61)

17q23

ACE or DCP1 (MIM 106180)

6.5

Leu33Pro (V62)

17q21.32

ITGB3 (MIM 173470)

0.32

15:

Cys112Arg (V63)

19q13.2

APOE (MIM 107741)

9.06

Arg158Cys (V64)

19q13.2

APOE

41.7

Ncol+/- (V65)

19p13.2

LDLR (MIM 606945)

0.97

Gly214Arg (V66)

19p13.3-13.21

ICAM1 (MIM 147840)

0

16:

844 68bp-/Ins (V67)

21q22.3

CBS (MIM 236200)

0.32

Ile278Thr (V68)

21q22.3

CBS

0.32


* See http://www.ncbi.nlm.nih.gov/Omim/ webcite.

van Greevenbroek et al. BMC Medical Genetics 2008 9:36   doi:10.1186/1471-2350-9-36

Open Data