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Heritability (h2) estimates, and standard error, for each quantitative trait for cardiovascular risk factors (in percentage), unadjusted (Model 1), adjusted for age, sex, age2, and age × sex interaction (Model 2), and adjusted for age, sex, age2, and age × sex interaction, and current medication (Model 3). |
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| Model 1* |
Model 2* |
Model 3* |
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| Waist circumference (cm) |
26.1(0.042) |
40.1(0.049) |
- |
| Fasting glucose (mg/dL)Δ |
32.8(0.046) |
34.5(0.047) |
32.3(0.047) |
| Triglycerides (mg/dL) |
25.7(0.044) |
28.8(0.048) |
28.4(0.048) |
| HDL-cholesterol (mg/dL) |
31.2(0.045) |
32.0(0.046) |
32.3(0.046) |
| Systolic blood pressure (mmHg)Δ |
15.0(0.036) |
25.9(0.042) |
20.6(0.042) |
| Diastolic blood pressure (mmHg)Δ |
16.4(0.037) |
26.2(0.044) |
21.0(0.044) |
| Total Cholesterol (mg/dL)Δ |
28.6(0.047) |
29.2(0.049) |
30.4(0.049) |
| LDL-cholesterol (mg/dL)Δ |
26.3(0.048) |
26.3(0.049) |
27.2(0.050) |
| BMI (kg/m2) |
39.1(0.045) |
51.0(0.048) |
- |
|
* p-value < 0.0001 Δ using tdist procedure in SOLAR | |||
de Oliveira et al. BMC Medical Genetics 2008 9:32 doi:10.1186/1471-2350-9-32 |
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