Table 2

Ontario Ministry of Health and Long-Term Care (MOHLTC) criteria for BRCA1 and BRCA2 genetic testing eligibility

Non-Ashkenazi Jewish

Ashkenazi Jewish


• Breast cancer <35 years

• Breast cancer <50 years

• Male breast cancer

• Breast cancer at any age with family history

• Serous ovarian cancer

• Unaffected individual with family history

• Breast cancer <60 years and family history of ovarian or male breast cancer

• Breast and ovarian cancer in same individual

• Bilateral breast cancer

• 2 cases breast cancer <50 years

• 2 cases ovarian cancer

• 3 cases breast cancer any age

• Known mutation

• Clinical judgment


Panchal et al. BMC Medical Genetics 2008 9:116   doi:10.1186/1471-2350-9-116

Open Data