This article is part of the supplement: The Framingham Heart Study 100,000 single nucleotide polymorphisms resource

Open Access Research

Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham study

Sudha Seshadri12*, Anita L DeStefano13, Rhoda Au12, Joseph M Massaro134, Alexa S Beiser123, Margaret Kelly-Hayes12, Carlos S Kase12, Ralph B D'Agostino14, Charles DeCarli5, Larry D Atwood12 and Philip A Wolf12

Author Affiliations

1 The National Heart Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA

2 Department of Neurology, Boston University School of Medicine, Boston, MA, USA

3 Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA

4 Statistics and Consulting Unit, Department of Mathematics, Boston University, Boston, MA, USA

5 The Department of Neurology, University of California – Davis, Sacramento, CA, USA

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BMC Medical Genetics 2007, 8(Suppl 1):S15  doi:10.1186/1471-2350-8-S1-S15

Published: 19 September 2007

Additional files

Additional file 1:

Details of test source and parameters used to define each individual test and factor are outlined in Additional Table 1. All SNPs within 60 kb of the candidate genes are listed in Additional Table 2.

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Open Data