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Inclusion and exclusion criteria for probands in the FISSIC program |
| a Inclusion criteria |
| 1. Diagnosis of at least one ischemic stroke confirmed by the study neurologist on the basis of history, medical records, and head imaging by CT or MRI; |
| 2. At least 18 years old by the time of enrolment in the study; |
| 3. At least one full sibling or parent alive in areas nearby; |
| 4. Written informed consent by the patient or surrogate. |
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| b Exclusion criteria |
| 1. Diagnosis of TIA only; |
| 2. Diagnosis of vasospasm after subarachnoid hemorrhage; |
| 3. Diagnosis of some Mendelian disorders: CADASIL, Fabry disease, MELAS, or sickle cell anaemia; |
| 4. Diagnosis of iatrogenic ischemic stroke associated with a surgical/interventional procedure such as coronary artery bypass grafting, carotid endarterectomy, or heart valve surgery; |
| 5. Diagnosis of ischemic stroke associated with autoimmune condition or endocarditis. |
Tang et al. BMC Medical Genetics 2007 8:60 doi:10.1186/1471-2350-8-60 |