Figure 4.

Hyperglycemia incidence, by age at baseline, in the DESIR population according to SNP -1,701A>G genotype (dominant model). The genotype is considered a risk factor present since birth. The time scale is represented by age (continuous scale). The proportions with overweight (A), obesity (B), hyperglycemia (C) and T2D (D) were calculated within each genotype to assess the impact of SNP-1,701A>G on incidence of all phenotypes studied. Hazard ratios and p values indicated were obtained from Cox proportional hazard survival analyses with age, sex (overweight and obesity) and BMI (hyperglycaemia and T2D) as covariates among AA and AG+GG carriers during the 9 years of follow-up.