Table 1

CCR5 genotype and allele frequencies among controls, RA patients and JIA patients

Controls no. (%)

RA no. (%)

OR (95% CI)

p

JIA no. (%)

OR (95% CI)

p

CCR5 genotype

Δ32/Δ32

6 (0.9)

9 (1.0)

1.13 (0.43–2.98)

0.81

3 (0.6)

0.67 (0.20–2.31)

0.53

Δ32/wt

136 (21.1)

156 (18.7)

0.86 (0.66–1.11)

0.24

93 (18.1)

0.83 (0.62–1.11)

0.20

wt/wt

503 (78.0)

671 (80.3)

1.15 (0.89–1.48)

0.28

419 (81.4)

1.23 (0.92–1.64)

0.16

CCR5 allele

Δ32

148 (11.5)

174 (10.4)

0.90 (0.71–1.13)

0.35

99 (9.7)

0.82 (0.63–1.07)

0.15

wt

1142 (88.5)

1498 (89.6)

931 (90.4)

RA: rheumatoid arthritis; JIA: juvenile idiopathic arthritis; N: number of individuals/chromosomes with the denoted genotype/allele; OR (95% CI): Odds ratio with corresponding 95% confidence interval; wt: wild type; Δ32: 32 bp deletion.

Lindner et al. BMC Medical Genetics 2007 8:33   doi:10.1186/1471-2350-8-33