|
CCR5 genotype and allele frequencies among controls, RA patients and JIA patients |
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| Controls no. (%) |
RA no. (%) |
OR (95% CI) |
p |
JIA no. (%) |
OR (95% CI) |
p |
|
| CCR5 genotype |
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|
|
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| Δ32/Δ32 |
6 (0.9) |
9 (1.0) |
1.13 (0.43–2.98) |
0.81 |
3 (0.6) |
0.67 (0.20–2.31) |
0.53 |
| Δ32/wt |
136 (21.1) |
156 (18.7) |
0.86 (0.66–1.11) |
0.24 |
93 (18.1) |
0.83 (0.62–1.11) |
0.20 |
| wt/wt |
503 (78.0) |
671 (80.3) |
1.15 (0.89–1.48) |
0.28 |
419 (81.4) |
1.23 (0.92–1.64) |
0.16 |
| CCR5 allele |
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| Δ32 |
148 (11.5) |
174 (10.4) |
0.90 (0.71–1.13) |
0.35 |
99 (9.7) |
0.82 (0.63–1.07) |
0.15 |
| wt |
1142 (88.5) |
1498 (89.6) |
931 (90.4) |
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|
RA: rheumatoid arthritis; JIA: juvenile idiopathic arthritis; N: number of individuals/chromosomes with the denoted genotype/allele; OR (95% CI): Odds ratio with corresponding 95% confidence interval; wt: wild type; Δ32: 32 bp deletion. | |||||||
Lindner et al. BMC Medical Genetics 2007 8:33 doi:10.1186/1471-2350-8-33 |
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